Stable expression of intracellular Notch suppresses v-Src-induced transformation in avian neural cells
نویسندگان
چکیده
منابع مشابه
Notch Signaling Activation Suppresses v-Src-Induced Transformation of Neural Cells by Restoring TGF-β-Mediated Differentiation
BACKGROUND We have been investigating how interruption of differentiation contributes to the oncogenic process and the possibility to reverse the transformed phenotype by restoring differentiation. In a previous report, we correlated the capacity of intracellular Notch (ICN) to suppress v-Src-mediated transformation of quail neuroretina (QNR/v-src(ts)) cells with the acquisition by these undiff...
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ژورنال
عنوان ژورنال: Oncogene
سال: 2006
ISSN: 0950-9232,1476-5594
DOI: 10.1038/sj.onc.1210124